despotismn.[Cf. F. despotisme.]1. The power, spirit, or principles of a despot; absolute control over others; tyrannical sway; tyranny.(Byron.)2. A government which is directed by a despot; a despotic monarchy; absolutism; autocracy.()Despotism . . . is the only form of government which may with safety to itself neglect the education of its infant poor. (Bp. Horsley.)